Patents & Research
Development of biochemically standardized extracts from fresh rhizomes of turmeric for treatment of diseases caused by hyperuricemia (U.S. Patent No: 8808768 B2)
This invention demonstrates the ethanol extracts of fresh rhizome of turmeric (Curcuma longa) strongly inhibit a key biological enzyme responsible for the production of uric acid. Based on the research data, a biochemical method is developed to standardize turmeric extracts/products, which has many applications, including, identification and development of effective turmeric products; use of turmeric extracts/products to prevent the production of harmful uric acid in diseases caused by hyperuricemia and gout.
Mechanism-based biochemical standardization of Resveratrol products and their uses thereof (U.S. Patent Pending)
The patent comprises methods inhibiting the key biological enzyme, adenosine deaminase, by resveratrol from grapes and mulberry wood extract; and biochemical standardization of resveratrol or mulberry products. Inhibition of adenosine deaminase causes tissue adenosine levels to increase by preventing its metabolism into harmful uric acid and superoxides. The standardized resveratrol and mulberry products are useful in hypertension, gout and superoxides-related cell-damage of body tissues.
Botanics has extensive research expertise in the study of cardiovascular drugs, e.g. aspirin, enalapril, dipyridamole (persantin), ticlopidine, adenosine, dilazep. Most importantly, discovered the role of the pituitary hormone, vasopressin in the gender differences, platelet thrombosis and cardiovascular effects.